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Adult stem cells are undifferentiated cellsfound throughout the body after development, that multiply by cell division to replenish dying cells and regenerate damaged tissues. Scientific interest in adult stem cells is centered on their ability to divide or self-renew indefinitely, and generate all the cell types of the organ from which they originate, potentially regenerating the entire organ from a few cells. They have mainly been studied in humans and model organisms such as mice and rats.
Jump to navigation. For many years, researchers have been seeking to understand the body's ability to repair and replace the cells and tissues of some organs, but not others. After years of work pursuing the how and why of seemingly indiscriminant cell repair mechanisms, scientists have now focused their attention on adult stem cells.
ZenBio, a pioneer in the adult stem cell field, delivers quality, cost-effective adipose-derived stem cells in large enough quantities to meet a wide range of project demands. Each lot is evaluated and qualified to remain undifferentiated in culture or to differentiate into osteoblasts, chondrocytes or adipocytes upon exposure to specific differentiation media formulations. As interest grows in the expanding field of stem cell research, areas such as regenerative medicine, tissue engineering and basic stem cell biology necessitate a reliable cost-effective cell-based tool for use in discovery and design projects. Adipose-derived adult stem cells and their unique differentiation properties can be utilized in any number of research applications and offer decided benefits over similar multipotent cell types.
Jump to navigation. An adult stem cell is thought to be an undifferentiated cell, found among differentiated cells in a tissue or organ. The adult stem cell can renew itself and can differentiate to yield some or all of the major specialized cell types of the tissue or organ.
For example, iPSC can be prodded into becoming beta islet cells to treat diabetes, blood cells to create new blood free of cancer cells for a leukemia patient, or neurons to treat neurological disorders. At that time, science had long understood that tissue specific cells, such as skin cells or blood cells, could only create other like cells. With this groundbreaking discovery, iPSC research has quickly become the foundation for a new regenerative medicine.
Some tissues in the adult body, such as the epidermis of the skin, the lining of the small intestineand bone marrowundergo continuous cellular turnover. The stem cells exist in niches formed by other cells, which secrete substances that keep the stem cells alive and active. Some types of tissue, such as liver tissue, show minimal cell division or undergo cell division only when injured. In such tissues there is probably no special stem-cell population, and any cell can participate in tissue regeneration when required.
Adult stem cells are undifferentiated cells found throughout the body that divide to replenish dying cells and regenerate damaged tissues. Research into adult stem cells has been fueled by their abilities to divide or self-renew indefinitely and generate all the cell types of the organ from which they originate — potentially regenerating the entire organ from a few cells. Unlike embryonic stem cells, the use of adult stem cells in research and therapy is not controversial because the production of adult stem cells does not require the destruction of an embryo.