No other potential conflicts of interest were reported by the authors, planners, reviewers, or staff managers of this article. Describe the urogenital consequences of antiestrogen treatment among women with a prior diagnosis of breast cancer and the effects that these side effects have on quality of life and medication compliance. Advise on the standard treatment of urogenital atrophy, including alternatives to topical estrogen replacement, in the non—breast cancer and breast cancer populations.
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Postmenopausal atrophic vaginitis, or vaginal atrophy, is the thinning of the walls of the vagina caused by decreased estrogen levels. This most commonly occurs after menopause. She also stops having menstrual periods.
The most common symptoms of vaginal atrophy are dryness, irritation, and pain during intercourse. Although menopause is the most common cause, vaginal atrophy can result from anything that lowers estrogen production. That includes chemotherapy, radiation, removal of the ovaries during hysterectomy, and use of anti-estrogenic therapies such as aromatase inhibitors, tamoxifen Nolvadexand drugs like leuprolide Lupron and nafarelin Synarelwhich are used to treat fibroids and endometriosis.
Many women experience vaginal atrophy during and after menopause. This condition, also sometimes called vulvovaginal atrophy VVAcauses vaginal:. VVA occurs when estrogen levels drop, as they do around the time a woman begins menopause.
A lot of changes happen when you reach the stage of life called menopause. You may discover that shifting levels of hormones — especially decreased amounts of estrogen produced by your body — bring new challenges. Vaginal atrophy is a common symptom of menopause.
The endocrine system is a network of glands and organs that produce, store, and secrete hormones. Menopause takes place gradually over four or five years. A woman may experience a number of uncomfortable symptoms during this time, including vaginal dryness.
Vaginal atrophy refers to inflammation, dryness, and thinning of the vaginal walls. While there are many treatments for vaginal atrophy, some people prefer a natural approach. This article examines some helpful natural remedies, lifestyle changes, and medical treatments that can reduce symptoms and enhance quality of life for women with vaginal atrophy. There are several lifestyle changes that could help women relieve the symptoms of vaginal atrophy.
Up to 40 percent of postmenopausal women have symptoms of atrophic vaginitis. Because the condition is attributable to estrogen deficiency, it may occur in pre-menopausal women who take antiestrogenic medications or who have medical or surgical conditions that result in decreased levels of estrogen. The thinned endometrium and increased vaginal pH level induced by estrogen deficiency predispose the vagina and urinary tract to infection and mechanical weakness.
Management of breast cancer includes systematic therapies including chemotherapy and endocrine therapy can lead to a variety of symptoms that can impair the quality of life of many breast cancer survivors. Atrophic vaginitis, caused by decreased levels of circulating estrogen to urinary and vaginal receptors, is commonly experienced by this group. Chemotherapy induced ovarian failure and endocrine therapies including aromatase inhibitors and selective estrogen receptor modulators can trigger the onset of atrophic vaginitis or exacerbate existing symptoms. Symptoms of atrophic vaginitis include vaginal dryness, dyspareunia, and irritation of genital skin, pruritus, burning, vaginal discharge, and soreness.