Skip to Content. Use the menu to see other pages. Although risk factors often influence the development of cancer, most do not directly cause cancer.
Breast cancer is a disease in which certain cells in the breast become abnormal and multiply uncontrollably to form a tumor. Although breast cancer is much more common in women, this form of cancer can also develop in men. In both women and men, the most common form of breast cancer begins in cells lining the milk ducts ductal cancer.
If you have close relatives with breast or ovarian cancer, you may be at higher risk for developing these diseases. Does your family health history put you at higher risk? Would you benefit from cancer genetic counseling and testing?
In this review, we provide an overview of hereditary breast cancer, its genetic background, and clinical implications, before focusing on the pathologically and molecular features associated with the disease. Breast cancer is the most frequent malignant disease and the leading cause of cancer death among women in both economically developed and developing countries. Globally, 1. Owing to increased awareness, early detection, and better treatment options available, breast cancer mortality rates have declined in recent years.
Find information and resources for current and returning patients. Learn about clinical trials at MD Anderson and search our database for open studies. The Lyda Hill Cancer Prevention Center provides cancer risk assessment, screening and diagnostic services.
Thinking about cancer or dealing with cancer risk can be scary or overwhelming, but we believe that receiving information and resources is comforting, empowering, and lifesaving. Every woman is at risk for breast cancer and her risk increases with age. This risk remains low before age 50; the majority of risk occurs after age
Who will be offered genetic testing? How is the test done? Getting your predictive genetic test results 4.
Genes are short segments of DNA deoxyribonucleic acid found in chromosomes. DNA contains the instructions for building proteins. And proteins control the structure and function of all the cells that make up your body.
An estimated 0. Family history is one of the unavoidable genetic risk factors for developing breast cancer. Ongoing research is helping identify the genes that are responsible for this inherited increased risk.
Everyone has these genes, but some people have an inherited mutation in one or both that increases the risk of breast cancer. The risk from different types of inherited gene mutations can vary greatly. Inherited mutations known to increase the risk of breast cancer are rare in the general population.